Recruitment
Most trials miss enrolment timelines. Screening remains slow, manual, and coordinator-heavy.
INTELLIGENCE FOR CLINICAL RESEARCH
Better trials.
Connected by
intelligence.
Less operational friction.
More room for human care.
The operational intelligence layer for clinical research — connecting participants, sites, and data from first contact to database lock.
Privacy by design Humans in control
ONE CONNECTEDINTELLIGENCE LAYER
AI ReceptionEvery connection counts.
History TakerReady before the visit.
AI ScribePresent. Not transcribing.
Trial IntelligenceClarity at every stage.
Four modules. One continuous flow.
BUILT AROUND THE ENTIRE TRIAL JOURNEYDiscover a more connected trial
01 / THE FRICTION AROUND THE SCIENCE
Trials stall on operations.
That’s where we come in.
Recruitment, retention, site burden, and data quality. Operational problems call for a connected operational response.
Retention
Participant dropout commonly reaches 20–30%, forcing costly over-recruitment and timeline slip.
Site burden
Coordinators and investigators lose hours every day to scheduling, documentation, and follow-up.
Data quality
Unstructured source notes create transcription work, data queries, and monitoring costs.
Challenges outlined in our 2026 clinical-trials overview.Read the overview ↗
02 / THE CONNECTED TRIAL
One ecosystem.
The entire protocol.
AI modules proven in day-to-day healthcare delivery, re-deployed across the trial lifecycle. One connected platform, from first contact to database lock.
Meet your operational layerAnd between visits? The connection continues.
Dosing and diary reminders. Symptom check-ins. A 24/7 line for questions. The same platform keeps participants engaged throughout.
BY DESIGN
Every interaction generates structured data.More value with every visit, at every site.
03 / YOUR OPERATIONAL ADVANTAGE
Four specialists.
One seamless ecosystem.
Purpose-built intelligence for the work around the science.
CONNECT / 01
A better first contact. A lasting connection.
From an initial screening call to the next appointment, give every participant a clear, supported path through your trial.
- Phone, WhatsApp, SMS, and web chat — 24/7
- Protocol-window booking and home-visit availability
- Dosing reminders, diary prompts, and retention outreach
PARTICIPANT SUPPORT
A little reassurance.
A clear next step.
Your next visitTuesday, 10:30 · Site appointment
Connected through every step
RECRUIT · SCHEDULE · RETAIN
24/7 multichannel participant engagement across phone, WhatsApp, SMS, and web chat.
What it does in a trial 8 capabilities
- Reach candidate participants by phone, WhatsApp, SMS, and web chat
- Pre-screen against inclusion and exclusion criteria before site contact
- Book, confirm, and remind for every protocol visit window
- Check attendance ahead of visits and follow up with non-responders
- Check availability for home visits and mobile phlebotomy
- Let participants reschedule instantly within the protocol window
- Run retention outreach: dosing reminders, diary prompts, and check-ins
- Answer questions 24/7 in the participant’s own language
Why it matters
- Deflect ineligible enquiries before they consume coordinator time
- Reduce no-shows by confirming visits and following up on every miss
- Reduce out-of-window visits and protocol deviations
- Catch dropout risk early through continuous engagement
- Keep recruitment running around the clock, beyond office hours
A missed visit means lost data, a possible protocol deviation, and a retention warning. Nurial closes the loop before the gap grows.
PREPARE / 02
Start the visit one step ahead.
Capture a structured history before the visit. Give coordinators the context they need and participants more time to be heard.
- Protocol-specific eligibility and interim history
- Adverse event and concomitant-medication review
- Guided ePRO, eDiary, and between-visit check-ins
Pre-visit summary
Structured intake · Example participant01Presenting history
02Current medications
03Eligibility criteria
04Questions for the site team
Prepared for clinical review
SCREEN · PREPARE · CAPTURE
Structured pre-visit data collection that makes every visit shorter and more complete.
What it does in a trial 6 capabilities
- Structured pre-screening questionnaires mapped to eligibility criteria
- Pre-visit capture of interim history before each protocol visit
- Adverse event and concomitant-medication review ahead of the visit
- Guided prompts for electronic patient-reported outcomes (ePRO) and electronic diaries (eDiary)
- Between-visit symptom and safety check-ins
- Consistent, standardised data capture at every site
Why it matters
- Investigators and nurses start every visit already informed
- Visit time goes to assessments rather than reconstructing what happened
- More complete histories help reduce missed adverse events and concomitant medications
- Standardised capture reduces site-to-site variability and queries
- Home and remote visits become as structured as on-site visits
The visit becomes confirmation and clinical judgement — not data collection from scratch.
DOCUMENT / 03
Be in the moment. Keep every detail.
Turn clinical conversations into structured documentation, with participant consent and clinician review at the centre.
- Source notes and documentation for every clinical role
- Structured, EDC-ready data and coding suggestions
- Authorised review and approval before entering the record
Consultation → structured record
“Let’s start with how you’ve been
feeling since your last visit.”
feeling since your last visit.”
SSubjective
OObjective
AAssessment
PPlan
Clinician review remains essential
DOCUMENT · CODE · COMPLY
Ambient documentation for investigators, research nurses, coordinators, phlebotomists, and home teams.
What it does in a trial 4 capabilities
- Capture contemporaneous, consistent, attributable documentation
- Capture information once for both the source record and trial database
- Prepare structured, EDC-ready data and coding suggestions for review
- Require review and approval by an authorised professional before any document enters the record
Why it matters
- Support every professional who touches a participant
- Keep clinical attention on the encounter
- Create a consistent documentation structure across roles and settings
- Keep professional judgement and approval at the centre
Documentation for every role.
Everyone who touches a participant. One consistent record.
Investigators
- Visit source notes
- Adverse event narratives and causality notes
- Protocol deviation notes
- GP and referral letters
Research nurses
- Assessment documentation
- Dosing and administration notes
- Safety observation records
- Participant education notes
Coordinators
- Visit reports and checklists
- Contact and follow-up logs
- Structured, EDC-ready data
- Coding suggestions for review
Phlebotomy & home teams
- Sample collection documentation
- Home-visit encounter notes
- Chain-of-custody detail capture
- Hands-free documentation on the move
Captured once. Structured for the source record and trial database. Reviewed and approved by an authorised professional.
UNDERSTAND / 04
See the whole trial. Act on what matters.
Connect the signals across sites, visits, and participants to understand operational performance and spot emerging risks.
- Enrolment and retention visibility
- Protocol deviation signals
- Cross-site performance benchmarking
One shared picture
Site performance · Illustrative dataVisit completion91.2%
Enrolled89
WEEK 01WEEK 08
Turn activity into actionable insight
MEASURE · PREDICT · OPTIMISE
A unified structured-data layer powering enrolment, retention, and site analytics for sponsors, CROs, and sites.
What it does in a trial 9 capabilities
- Enrolment funnel and conversion
- Screen-failure patterns
- Visit completion and no-show rates
- Retention risk flags
- Protocol deviation trends
- Data query rates by site
- Site performance benchmarking
- Home-visit logistics and coverage
- Per-visit cost and budget tracking
Why it matters
- See operational activity as the trial runs, rather than relying on month-old status reports
- Bring the signals from every module into one structured platform
- Build a richer intelligence layer with every additional site, visit, and module
- Use real operational data to inform feasibility, site selection, and forecasting for the next trial
Every interaction generates structured data. The platform becomes more valuable with every visit, at every site.
More continuity for participants. More capacity for your team.
CONNECTED BY DESIGN04 / THE BIGGER PICTURE
Every signal.
One clear view.
Your trial tells a story. Connect the data across every site and participant to see what needs your attention.
Intelligence that compounds with every visit
NURIAL WORKSPACE
SAMPLE DATATrial overview / Command centre
Illustrative 8-week view
Enrolment momentum
247 screened89participants enrolled
WEEK 01WEEK 02WEEK 04WEEK 06WEEK 08
Visit completion
91.2% On trackParticipants flagged
7 For reviewData queries / visit
1.4 38% below baselineLess time piecing it together.
More time moving it forward.
NINE VIEWS. ONE OPERATIONAL TRUTH.
For sponsors, contract research organisations (CROs), and sites. Live operational insight, rather than month-old status reports.
01Enrolment funnel and conversion
02Screen-failure patterns
03Visit completion and no-show rates
04Retention risk flags
05Protocol deviation trends
06Data query rates by site
07Site performance benchmarking
08Home-visit logistics and coverage
09Per-visit cost and budget tracking
The next trial starts smarter.
Every additional site, visit, and module enriches the same intelligence layer. Feasibility, site selection, and forecasting for the next trial start from real operational data, rather than estimates.
05 / BUILT FOR MODERN TRIALS
Beyond the site.
Without losing the picture.
Hybrid, decentralised, and diverse by design. The same structured approach, wherever care happens.
Decentralised & hybrid trials
- Home-visit scheduling with participant availability checks
- Mobile phlebotomy coordination and documentation
- Remote structured check-ins between site visits
- The same data structure on-site, at home, and remotely
Diverse, global populations
- Multilingual engagement across phone, WhatsApp, and SMS
- Works with EHRs where available and paper workflows where they are not
- Built on a platform live in hospitals and clinics across Africa, the Middle East, and Asia
- A practical route to the diverse enrolment sponsors are asked to deliver
PRIVACY-FIRST BY DESIGN
Your data. Your control.
- Organisation-owned data
- Encrypted in transit and at rest
- Role-based access and full audit logs
- Professional judgement always
06 / THE OPERATIONAL CASE
Better for your team.
Better for your trial.
What could connected operations be worth on one Phase III trial? Explore the illustrative scenario from our clinical-trials overview.
NUMBER OF SITES
400 randomised participants4,800 visits
12 visits per participant3:1 screening ratio
All figures in US dollars. The original scenario uses 40 sites, 400 randomised participants, and 4,800 visits. Changing site count scales its rounded savings proportionally; it is an illustration, not a forecast or pricing quote.
Model your own protocol and budgetILLUSTRATIVE OPERATIONAL SAVINGPHASE III · USD
APPROXIMATELYUS$854,000across the trial lifecycle
Automated pre-screeningUS$163,000
Reminders & self-serve reschedulingUS$144,000
Retention engagementUS$300,000
Pre-visit history captureUS$54,000
Ambient documentationUS$139,000
Data qualityUS$54,000
Rounded scenario estimates · Adjustable to your protocol
INSIDE THE MODELExplore all six savings assumptions.Original 40-site scenario · 400 participants · 4,800 visits · USD
The original overview describes conservative, adjustable assumptions. These are the baseline figures behind the calculator, shown at 40 sites regardless of your selected scenario.
| Operational lever | Illustrative assumption | Saving (USD) |
|---|---|---|
| Automated pre-screening | Approximately 6,000 enquiries triaged for 1,200 screening visits. Ineligible enquiries are deflected before coordinator contact (approximately 1,500 hours saved), and on-site screen failures are reduced by approximately 10% (80 × US$1,200). | US$163,000 |
| Reminders & self-serve rescheduling | Missed-visit rate falls from 12% to 7% across 4,800 visits: 240 avoided misses at approximately US$600 each, including site time, rebooking, and deviation handling. | US$144,000 |
| Retention engagement | Dropout falls from 25% to 20%: 20 participants retained at approximately US$15,000 replacement cost each, covering recruitment, screening, and repeat early visits. | US$300,000 |
| Pre-visit history capture | Approximately 15 minutes of clinical staff time saved per visit across 4,800 visits, with staff time valued at US$45 per hour. | US$54,000 |
| Ambient documentation | Approximately 20 minutes saved per visit: 8 minutes of investigator time at US$150 per hour plus 12 minutes of site staff time at US$45 per hour, across 4,800 visits. | US$139,000 |
| Data quality | Query rate falls from 0.50 to 0.35 per visit: approximately 720 queries avoided at approximately US$75 handling cost each. | US$54,000 |
| Total illustrative saving per trial | ≈ US$854,000 | |
And the opportunity beyond the spreadsheet? Faster enrolment and fewer lost participants can shorten the trial itself. Time saved may be worth more than the direct operational savings above.
07 / THE NURIAL PRINCIPLE
Proven in care delivery.
Ready for research.
Clinical research is complex.
The principles behind our technology shouldn’t be.
Intelligence that supports care.
Never replaces it.
OF ARTIFICIAL INTELLIGENCE
NURIAL AIAI for
Clinical Trials.CLINICAL-TRIALS OVERVIEW / 2026
Clinical Trials.CLINICAL-TRIALS OVERVIEW / 2026
THE COMPLETE PICTURE
Take the thinking
to your team.
The full 12-page clinical-trials overview: every module, every role, the end-to-end workflow, and the assumptions behind the operational case.
08 / WHAT COMES NEXT
Your next trial.
A new
possibility.
Let’s map Nurial to your next protocol. A working session with your operations team is enough to model the impact — site by site, visit by visit, against your own protocol and budget.
info@nurial.co.uk A conversation about your trial. A plan built around it.
LET’S BUILD SOMETHING BETTER
Start a conversation.
Tell us a little about what you’re working on.